PDBe 2ixg

X-ray diffraction
2.7Å resolution

Crystal structure of the ATPase domain of TAP1 with ATP (S621A, G622V, D645N mutant)


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Antigen peptide transporter 1 Chain: A
Molecule details ›
Chain: A
Length: 271 amino acids
Theoretical weight: 29.51 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P36370 (Residues: 465-725; Coverage: 36%)
Gene names: Abcb2, Mtp1, Tap1
Sequence domains: ABC transporter
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P41212
Unit cell:
a: 67.477Å b: 67.477Å c: 105.903Å
α: 90° β: 90° γ: 90°
R R work R free
0.217 0.212 0.267
Expression system: Escherichia coli BL21(DE3)