PDBe 2ixe

X-ray diffraction
2Å resolution

Crystal structure of the ATPase domain of TAP1 with ATP (D645N mutant)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Antigen peptide transporter 1 Chains: A, D
Molecule details ›
Chains: A, D
Length: 271 amino acids
Theoretical weight: 29.48 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P36370 (Residues: 465-725; Coverage: 36%)
Gene names: Abcb2, Mtp1, Tap1
Sequence domains: ABC transporter
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P41212
Unit cell:
a: 80.431Å b: 80.431Å c: 168.115Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.199 0.241
Expression system: Escherichia coli BL21(DE3)