PDBe 2ix7

X-ray diffraction
2.5Å resolution

Structure of apo-calmodulin bound to unconventional myosin V

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Unconventional myosin-Va Chain: C
Molecule details ›
Chain: C
Length: 58 amino acids
Theoretical weight: 6.92 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q99104 (Residues: 763-820; Coverage: 3%)
Gene names: Dilute, Myo5a
Sequence domains: IQ calmodulin-binding motif
Calmodulin-3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 145 amino acids
Theoretical weight: 16.45 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P0DP28 (Residues: 3-147; Coverage: 97%)
Gene names: Calm3, Cam3, Camc

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P3221
Unit cell:
a: 112Å b: 112Å c: 102.34Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.216 0.259
Expression system: Escherichia coli BL21