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Human tACE g13 mutant

X-ray diffraction
2.01Å resolution
PDB entry 2iul coloured by chain, front view.
PDB entry 2iul coloured by chain, side view.
PDB entry 2iul coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Angiotensin-converting enzyme, soluble form
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Multimeric state: monomeric
Accessible surface area: 23911.74 Å2
Buried surface area: 2234.76 Å2
Dissociation area: 101.91 Å2
Dissociation energy (ΔGdiss): 2.33 kcal/mol
Dissociation entropy (TΔSdiss): -0.35 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-146325

Macromolecules

Angiotensin-converting enzyme, soluble form
Chain: A
Length: 591 amino acids
Theoretical weight: 68.35 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P12821 (Residues: 642-1232; Coverage: 46%)
Gene names: ACE, DCP, DCP1
Pfam: Angiotensin-converting enzyme
InterPro: Peptidase M2, peptidyl-dipeptidase A
Angiotensin-converting enzyme, soluble form in PDB entry 2iul, assembly 1, front view.
Angiotensin-converting enzyme, soluble form in PDB entry 2iul, assembly 1, side view.
Angiotensin-converting enzyme, soluble form in PDB entry 2iul, assembly 1, top view.
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