Structure analysis

CRYSTAL STRUCTURE OF THE PI3-KINASE P85 N-TERMINAL SH2 DOMAIN

X-ray diffraction
1.89Å resolution
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: monomeric

Binding statistics and energies are not available for this assembly

Macromolecules

Chain: A
Length: 120 amino acids
Theoretical weight: 13.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P27986 (Residues: 321-440; Coverage: 17%)
  • Best match: P27986-5 (Residues: 1-77)
Gene names: GRB1, PIK3R1
Pfam: SH2 domain
InterPro:
CATH: SHC Adaptor Protein

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