PDBe 2it4

X-ray diffraction
2Å resolution

X ray structure of the complex between Carbonic Anhydrase I and the phosphonate antiviral drug foscarnet

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carbonic anhydrase 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 256 amino acids
Theoretical weight: 28.4 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P00915 (Residues: 6-261; Coverage: 98%)
Gene name: CA1
Structure domains: Carbonic Anhydrase II

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: OXFORD DIFFRACTION ENHANCED ULTRA
Spacegroup: P212121
Unit cell:
a: 62.58Å b: 69.51Å c: 120.44Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.249 0.246 0.316