PDBe 2ipi

X-ray diffraction
1.65Å resolution

Crystal Structure of Aclacinomycin Oxidoreductase

Released:

Function and Biology Details

Reactions catalysed:
Aclacinomycin N + O(2) = aclacinomycin A + H(2)O(2)
Aclacinomycin A + O(2) = aclacinomycin Y + H(2)O(2)
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aclacinomycin-N/aclacinomycin-A oxidase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 521 amino acids
Theoretical weight: 57.22 KDa
Source organism: Streptomyces galilaeus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q0PCD7 (Residues: 44-545; Coverage: 100%)
Gene name: aknOx
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P21
Unit cell:
a: 68.5Å b: 266.2Å c: 68.7Å
α: 90° β: 119° γ: 90°
R-values:
R R work R free
0.185 not available 0.242
Expression system: Escherichia coli