› 2ihr

X-ray diffraction
2.5Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178228 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptide chain release factor RF2 Chain: 1
Molecule details ›
Chain: 1
Length: 365 amino acids
Theoretical weight: 41.36 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5SM01 (Residues: 27-378; Coverage: 93%)
Gene names: TTHA0142, prfB
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P41212
Unit cell:
a: 144.65Å b: 144.65Å c: 54.47Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.269 0.269 0.317
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

7 review citations

Peptide release on the ribosome: mechanism and implications for translational control.
Youngman et al. (2008)
6 more

4 mentions without citation

A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome.
Richter et al. (2010)
3 more