PDBe 2i2r

X-ray diffraction
3.35Å resolution

Crystal structure of the KChIP1/Kv4.3 T1 complex

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero octamer (preferred)
hetero 16-mer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Kv channel-interacting protein 1 Chains: E, F, G, H, M, N, O, P
Molecule details ›
Chains: E, F, G, H, M, N, O, P
Length: 180 amino acids
Theoretical weight: 21.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NZI2 (Residues: 48-227; Coverage: 79%)
Gene names: KCHIP1, KCNIP1, VABP
Sequence domains:
Structure domains: EF-hand
Potassium voltage-gated channel subfamily D member 3 Chains: A, B, C, D, I, J, K, L
Molecule details ›
Chains: A, B, C, D, I, J, K, L
Length: 144 amino acids
Theoretical weight: 16.81 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q62897 (Residues: 2-143; Coverage: 22%)
Gene name: Kcnd3
Sequence domains:
Structure domains: Potassium Channel Kv1.1; Chain A

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P1
Unit cell:
a: 93.151Å b: 98.105Å c: 97.783Å
α: 91° β: 112.56° γ: 111.77°
R-values:
R R work R free
0.238 0.237 0.268
Expression system: Escherichia coli