PDBe 2hzn

X-ray diffraction
2.7Å resolution

Abl kinase domain in complex with NVP-AFG210

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase ABL1 Chain: A
Molecule details ›
Chain: A
Length: 293 amino acids
Theoretical weight: 33.74 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P00520 (Residues: 229-515; Coverage: 26%)
Gene names: Abl, Abl1
Sequence domains: Protein tyrosine kinase
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: I4122
Unit cell:
a: 105.431Å b: 105.431Å c: 110.358Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.267 0.264 0.314
Expression system: Spodoptera frugiperda