PDBe 2hqj

X-ray diffraction
2Å resolution

Cyclophilin from Leishmania major

Released:
Source organism: Leishmania major
Entry authors: Arakaki TL, Merritt EA, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidyl-prolyl cis-trans isomerase Chain: A
Molecule details ›
Chain: A
Length: 183 amino acids
Theoretical weight: 19.47 KDa
Source organism: Leishmania major
Expression system: Escherichia coli
UniProt:
  • Canonical: Q4QBH1 (Residues: 22-199; Coverage: 60%)
Gene names: CYP11, LMJF_23_0050
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Structure domains: Cyclophilin-like

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P212121
Unit cell:
a: 45.865Å b: 63.511Å c: 66.295Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.191 0.239
Expression system: Escherichia coli