PDBe 2he9

X-ray diffraction
2Å resolution

Structure of the peptidylprolyl isomerase domain of the human NK-tumour recognition protein

Released:
Source organism: Homo sapiens
Entry authors: Walker JR, Davis T, Newman EM, MacKenzie F, Butler-Cole C, Finerty Jr PJ, Weigelt J, Sundstrom M, Arrowsmith CH, Edwards AM, Bochkarev A, Dhe-Paganon S, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NK-tumor recognition protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 192 amino acids
Theoretical weight: 21.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P30414 (Residues: 7-179; Coverage: 12%)
Gene name: NKTR
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P21212
Unit cell:
a: 64.753Å b: 72.786Å c: 73.014Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.149 0.146 0.198
Expression system: Escherichia coli BL21(DE3)