PDBe 2hda

X-ray diffraction
1.9Å resolution

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo hexamer
homo trimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase Yes Chain: A
Molecule details ›
Chain: A
Length: 64 amino acids
Theoretical weight: 7.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P07947 (Residues: 91-152; Coverage: 11%)
Gene names: YES, YES1
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR
Spacegroup: P6322
Unit cell:
a: 46.009Å b: 46.009Å c: 90.431Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.22 0.214 0.27
Expression system: Escherichia coli