PDBe 2hbj

X-ray diffraction
2.1Å resolution

Structure of the yeast nuclear exosome component, Rrp6p, reveals an interplay between the active site and the HRDC domain

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Exosome complex exonuclease RRP6 Chain: A
Molecule details ›
Chain: A
Length: 410 amino acids
Theoretical weight: 47.68 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: Q12149 (Residues: 129-536; Coverage: 56%)
Gene names: RRP6, UNC733, YOR001W
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7A, EMBL/DESY, HAMBURG BEAMLINE X13
Spacegroup: P3121
Unit cell:
a: 110.135Å b: 110.135Å c: 80.169Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.239 0.232 0.292
Expression system: Escherichia coli