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Solution structure of the helicase-binding domain of Escherichia coli primase

Source organism: Escherichia coli
Biochemical function: DNA primase activity
Biological process: DNA replication, synthesis of primer
Cellular component: not assigned

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EC 2.7.7.101: DNA primase DnaG

Reaction catalysed:
SsDNA + n NTP = ssDNA/pppN(pN)(n-1) hybrid + (n-1) diphosphate
Systematic name:
Nucleotide 5'-triphosphate:single-stranded DNA nucleotidyltransferase (DNA-RNA hybrid synthesizing)
Alternative Name(s):
  • DnaG

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF08278
Domain description: DNA primase DnaG DnaB-binding
Occurring in:
  1. DNA primase
The deposited structure of PDB entry 2haj contains 1 copy of Pfam domain PF08278 (DNA primase DnaG DnaB-binding) in DNA primase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR013173
Domain description: DNA primase DnaG, DnaB-binding domain
Occurring in:
  1. DNA primase
IPR016136
Domain description: DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal
Occurring in:
  1. DNA primase

Structure domain

CATH CATH domain
1.10.860.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: DNAb Helicase; Chain A
Homology: DNAb Helicase; Chain A
Occurring in:
  1. DNA primase
The deposited structure of PDB entry 2haj contains 1 copy of CATH domain 1.10.860.10 (DNAb Helicase; Chain A) in DNA primase. Showing 1 copy in chain A.
SCOP SCOP annotation
117024
Class: All alpha proteins
Fold: DNA primase DnaG, C-terminal domain
Superfamily: DNA primase DnaG, C-terminal domain
Occurring in:
  1. DNA primase
The deposited structure of PDB entry 2haj contains 1 copy of SCOP domain 117024 (DNA primase DnaG, C-terminal domain) in DNA primase. Showing 1 copy in chain A.

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