PDBe 2h8h

X-ray diffraction
2.2Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proto-oncogene tyrosine-protein kinase Src Chain: A
Molecule details ›
Chain: A
Length: 535 amino acids
Theoretical weight: 59.86 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P12931 (Residues: 2-536; Coverage: 100%)
Gene names: SRC, SRC1
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P212121
Unit cell:
a: 49.806Å b: 72.467Å c: 171.566Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.204 0.272
Expression system: Spodoptera frugiperda