PDBe 2h61

X-ray diffraction
1.9Å resolution

X-ray structure of human Ca2+-loaded S100B

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein S100-B Chains: A, B, E, F, H
Molecule details ›
Chains: A, B, E, F, H
Length: 92 amino acids
Theoretical weight: 10.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P04271 (Residues: 1-92; Coverage: 100%)
Gene name: S100B
Sequence domains:
Structure domains: EF-hand
Protein S100-B Chains: C, D, G
Molecule details ›
Chains: C, D, G
Length: 92 amino acids
Theoretical weight: 10.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P04271 (Residues: 1-92; Coverage: 100%)
Gene name: S100B
Sequence domains:
Structure domains: EF-hand

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SIEMENS
Spacegroup: P21
Unit cell:
a: 63.4Å b: 81.6Å c: 71.5Å
α: 90° β: 107° γ: 90°
R-values:
R R work R free
0.177 0.174 0.241
Expression system: Escherichia coli BL21(DE3)