EC 3.4.22.56: Caspase-3
Reaction catalysed:
Strict requirement for an Asp residue at positions P1 and P4. It has a preferred cleavage sequence of Asp-Xaa-Xaa-Asp-|- with a hydrophobic amino-acid residue at P2 and a hydrophilic amino-acid residue at P3, although Val or Ala are also accepted at this position
Systematic name:
-
Alternative Name(s):
- Apopain
- CASP-3
- CPP32
- Yama protein
GO terms
Biochemical function:
Biological process:
Cellular component:
- not assigned
Protein family (Pfam)
InterPro annotations
CATH domains
