PDBe 2gtr

X-ray diffraction
1.9Å resolution

Human chromodomain Y-like protein

Released:
Source organism: Homo sapiens
Entry authors: Min J, Wu H, Antoshenko T, Loppnau P, Weigelt J, Sundstrom M, Arrowsmith CH, Edwards AM, Bochkarev A, Plotnikov AN, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed:
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chromodomain Y-like protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 261 amino acids
Theoretical weight: 29.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y232 (Residues: 338-598; Coverage: 44%)
Gene names: CDYL, CDYL1
Sequence domains: Enoyl-CoA hydratase/isomerase
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: C2
Unit cell:
a: 76.207Å b: 132.739Å c: 100.361Å
α: 90° β: 102.92° γ: 90°
R-values:
R R work R free
0.191 0.189 0.233
Expression system: Escherichia coli