› 2grj

X-ray diffraction
2.6Å resolution

Crystal structure of Dephospho-CoA kinase (EC 2.7.1.24) (Dephosphocoenzyme A kinase) (tm1387) from THERMOTOGA MARITIMA at 2.60 A resolution

Released:
DOI: 10.2210/pdb2grj/pdb
PDB entry 2grj coloured by chain, front view.
PDB entry 2grj coloured by chain, side view.
PDB entry 2grj coloured by chain, top view.
Source organism: Thermotoga maritima
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
ATP + 3'-dephospho-CoA = ADP + CoA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194778 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dephospho-CoA kinase Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 192 amino acids
Theoretical weight: 22.06 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9X1A7 (Residues: 1-180; Coverage: 100%)
Gene names: TM_1387, coaE
Sequence domains: Dephospho-CoA kinase
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

3 bound ligands:
Ligand ADP 8 x ADP
Ligand COD 8 x COD
Ligand CL 4 x CL
1 modified residue:
Ligand MSE 40 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-ID-B
Spacegroup: P21
Unit cell:
a: 90.832Å b: 87.217Å c: 98.586Å
α: 90° β: 106.92° γ: 90°
R-values:
R R work R free
0.193 0.191 0.245
Expression system: Escherichia coli

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