PDBe 2gmv

X-ray diffraction
2.3Å resolution

PEPCK complex with a GTP-competitive inhibitor

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Chains: A, B
Molecule details ›
Chains: A, B
Length: 625 amino acids
Theoretical weight: 69.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P35558 (Residues: 1-622; Coverage: 100%)
Gene names: PCK1, PEPCK1
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X8C
Spacegroup: P21
Unit cell:
a: 128.011Å b: 66.134Å c: 137.36Å
α: 90° β: 145.09° γ: 90°
R-values:
R R work R free
0.217 0.217 0.287
Expression system: Escherichia coli