PDBe 2gl8

X-ray diffraction
2.4Å resolution

Human Retinoic acid receptor RXR-gamma ligand-binding domain

Released:
Source organism: Homo sapiens
Entry authors: Min JR, Schuetz A, Loppnau P, Weigelt J, Sundstrom M, Arrowsmith CH, Edwards AM, Bochkarev A, Plotnikov AN, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Retinoic acid receptor RXR-gamma Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 241 amino acids
Theoretical weight: 27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P48443 (Residues: 227-463; Coverage: 51%)
Gene names: NR2B3, RXRG
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P21
Unit cell:
a: 48.07Å b: 161.316Å c: 68.682Å
α: 90° β: 109.5° γ: 90°
R-values:
R R work R free
0.245 0.243 0.296
Expression system: Escherichia coli