PDBe 2ghu

X-ray diffraction
3.1Å resolution

Crystal structure of falcipain-2 from Plasmodium falciparum

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Falcipain 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 241 amino acids
Theoretical weight: 27.19 KDa
Source organism: Plasmodium falciparum
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9N6S8 (Residues: 244-484; Coverage: 50%)
Sequence domains: Papain family cysteine protease
Structure domains: Cysteine proteinases

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X13
Spacegroup: C2221
Unit cell:
a: 145.83Å b: 168.28Å c: 178.09Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.231 0.231 0.274
Expression system: Escherichia coli