PDBe 2ggm

X-ray diffraction
2.35Å resolution

Human centrin 2 xeroderma pigmentosum group C protein complex

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Centrin-2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 172 amino acids
Theoretical weight: 20.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P41208 (Residues: 1-172; Coverage: 100%)
Gene names: CALT, CEN2, CETN2
Sequence domains: EF-hand domain pair
DNA repair protein complementing XP-C cells Chains: C, D
Molecule details ›
Chains: C, D
Length: 17 amino acids
Theoretical weight: 2.11 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q01831 (Residues: 847-863; Coverage: 2%)
Gene names: XPC, XPCC

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12B
Spacegroup: C2
Unit cell:
a: 59.15Å b: 59Å c: 104.24Å
α: 90° β: 94.3° γ: 90°
R-values:
R R work R free
0.194 0.192 0.245
Expression systems:
  • Escherichia coli
  • Not provided