Assemblies
Assembly Name:
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
Multimeric state:
homo dimer
Accessible surface area:
19966.4 Å2
Buried surface area:
7163.08 Å2
Dissociation area:
2,413.8
Å2
Dissociation energy (ΔGdiss):
30.82
kcal/mol
Dissociation entropy (TΔSdiss):
13.6
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-147362
Macromolecules
Chain: A
Length: 267 amino acids
Theoretical weight: 29.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: short chain dehydrogenase
InterPro:
SCOP: Tyrosine-dependent oxidoreductases
Length: 267 amino acids
Theoretical weight: 29.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P15428 (Residues: 3-256; Coverage: 96%)
Pfam: short chain dehydrogenase
InterPro:
- NAD(P)-binding domain superfamily
- Short-chain dehydrogenase/reductase SDR
- Short-chain dehydrogenase/reductase, conserved site
SCOP: Tyrosine-dependent oxidoreductases
![15-hydroxyprostaglandin dehydrogenase [NAD(+)] in PDB entry 2gdz, assembly 1, front view.](https://www.ebi.ac.uk/pdbe/static/entry/2gdz_entity_1_front_image-200x200.png "Homo dimeric assembly 1 of PDB entry <span class='highlight'>2gdz</span> contains 2 copies of <span class='highlight'>15-hydroxyprostaglandin dehydrogenase [NAD(+)]</span>. Front view.")
![15-hydroxyprostaglandin dehydrogenase [NAD(+)] in PDB entry 2gdz, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/2gdz_entity_1_side_image-200x200.png "Homo dimeric assembly 1 of PDB entry <span class='highlight'>2gdz</span> contains 2 copies of <span class='highlight'>15-hydroxyprostaglandin dehydrogenase [NAD(+)]</span>. Side view.")
![15-hydroxyprostaglandin dehydrogenase [NAD(+)] in PDB entry 2gdz, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/2gdz_entity_1_top_image-200x200.png "Homo dimeric assembly 1 of PDB entry <span class='highlight'>2gdz</span> contains 2 copies of <span class='highlight'>15-hydroxyprostaglandin dehydrogenase [NAD(+)]</span>. Top view.")