› 2gaa

X-ray diffraction
1.95Å resolution

Crystal structure of YFH7 from Saccharomyces cerevisiae: a putative P-loop containing kinase with a circular permutation.

Released:
DOI: 10.2210/pdb2gaa/pdb
PDB entry 2gaa coloured by chain, front view.
PDB entry 2gaa coloured by chain, side view.
PDB entry 2gaa coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Crystal structure and functional analysis identify the P-loop containing protein YFH7 of Saccharomyces cerevisiae as an ATP-dependent kinase.
Gueguen-Chaignon V, Chaptal V, Larivière L, Costa N, Lopes P, Morera S, Nessler S
Proteins 71 804-12 (2008)
PMID: 18004758

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155099 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-dependent kinase YFH7 Chain: A
Molecule details ›
Chain: A
Length: 359 amino acids
Theoretical weight: 41 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P43591 (Residues: 1-353; Coverage: 100%)
Gene names: AIM12, YFH7, YFR007W
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
1 modified residue:
Ligand CME 3 x CME

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: R3
Unit cell:
a: 134.756Å b: 134.756Å c: 48.679Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.193 0.193 0.232
Expression system: Escherichia coli

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