PDBe 2fot

X-ray diffraction
2.45Å resolution

Crystal structure of the complex between calmodulin and alphaII-spectrin

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calmodulin Chain: A
Molecule details ›
Chain: A
Length: 148 amino acids
Theoretical weight: 16.72 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P62157 (Residues: 2-149; Coverage: 99%)
Gene names: CALM, CAM
Sequence domains: EF-hand domain pair
Spectrin alpha chain, non-erythrocytic 1 Chain: C
Molecule details ›
Chain: C
Length: 42 amino acids
Theoretical weight: 4.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13813 (Residues: 1172-1190, 1191-1210; Coverage: 2%)
Gene names: NEAS, SPTA2, SPTAN1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P212121
Unit cell:
a: 44.288Å b: 57.737Å c: 69.753Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.245 0.245 0.269
Expression system: Escherichia coli