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Trypanosoma Rangeli Sialidase In Complex With 2,3- Difluorosialic Acid (Covalent Intermediate)

X-ray diffraction
2.2Å resolution
PDB entry 2fhr coloured by chain, front view.
PDB entry 2fhr coloured by chain, side view.
PDB entry 2fhr coloured by chain, top view.
Source organism: Trypanosoma rangeli
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Sialidase domain-containing protein
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-129183

Macromolecules

Sialidase domain-containing protein
Chain: A
Length: 652 amino acids
Theoretical weight: 71.21 KDa
Source organism: Trypanosoma rangeli
Expression system: Escherichia coli
UniProt:
  • Canonical: O44049 (Residues: 23-660; Coverage: 100%)
Pfam: BNR repeat-like domain
InterPro:
CATH:
SCOP:
Sialidase domain-containing protein in PDB entry 2fhr, assembly 1, front view.
Sialidase domain-containing protein in PDB entry 2fhr, assembly 1, side view.
Sialidase domain-containing protein in PDB entry 2fhr, assembly 1, top view.
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