› 2fg8

X-ray diffraction
2.5Å resolution

Structure of Human Ferritin L Chain

Released:
DOI: 10.2210/pdb2fg8/pdb
PDB entry 2fg8 coloured by chain, front view.
PDB entry 2fg8 coloured by chain, side view.
PDB entry 2fg8 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of human ferritin L chain.
Wang Z, Li C, Ellenburg M, Soistman E, Ruble J, Wright B, Ho JX, Carter DC
Acta Crystallogr D Biol Crystallogr 62 800-6 (2006)
PMID: 16790936

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo 24-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136239 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ferritin light chain Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 174 amino acids
Theoretical weight: 19.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02792 (Residues: 2-175; Coverage: 99%)
Gene name: FTL
Sequence domains: Ferritin-like domain
Structure domains: Ferritin

Ligands and Environments

1 bound ligand:
Ligand CS 10 x CS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12B
Spacegroup: R32
Unit cell:
a: 182.786Å b: 182.786Å c: 354.234Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.224 0.224 0.267
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Ferritin family proteins and their use in bionanotechnology.
He et al. (2015)
3 more

6 mentions without citation

Iron, Ferritin, Hereditary Ferritinopathy, and Neurodegeneration.
Muhoberac et al. (2019)
5 more