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Crystal structure of Fus3 without a peptide from Ste5

X-ray diffraction
2.85Å resolution
PDB entry 2fa2 coloured by chain, front view.
PDB entry 2fa2 coloured by chain, side view.
PDB entry 2fa2 coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Mitogen-activated protein kinase FUS3
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Multimeric state: homo dimer
Accessible surface area: 28464.26 Å2
Buried surface area: 4009.73 Å2
Dissociation area: 1,494.93 Å2
Dissociation energy (ΔGdiss): 12.13 kcal/mol
Dissociation entropy (TΔSdiss): 13.95 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-147838

Macromolecules

Mitogen-activated protein kinase FUS3
Chains: A, B
Length: 353 amino acids
Theoretical weight: 40.81 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P16892 (Residues: 1-353; Coverage: 100%)
Gene names: DAC2, FUS3, YBL016W, YBL03.21, YBL0303
Pfam: Protein kinase domain
InterPro:
CATH:
Mitogen-activated protein kinase FUS3 in PDB entry 2fa2, assembly 1, front view.
Mitogen-activated protein kinase FUS3 in PDB entry 2fa2, assembly 1, side view.
Mitogen-activated protein kinase FUS3 in PDB entry 2fa2, assembly 1, top view.
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