PDBe 2f73

X-ray diffraction
2.5Å resolution

Crystal structure of human fatty acid binding protein 1 (FABP1)

Released:
Source organism: Homo sapiens
Entry authors: Kursula P, Thorsell AG, Arrowsmith C, Berglund H, Edwards A, Ehn M, Flodin S, Graslund S, Hammarstrom M, Holmberg Schiavone L, Kotenyova T, Nilsson-Ehle P, Nordlund P, Nyman T, Ogg D, Persson C, Sagemark J, Stenmark P, Sundstrom M, van den Berg S, Weigelt J, Hallberg BM, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein, liver Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 149 amino acids
Theoretical weight: 16.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P07148 (Residues: 1-127; Coverage: 100%)
Gene names: FABP1, FABPL
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P212121
Unit cell:
a: 76.052Å b: 78.134Å c: 235.112Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.25 0.25 0.286
Expression system: Escherichia coli