PDBe 2f57

X-ray diffraction
1.8Å resolution

Crystal Structure Of The Human P21-Activated Kinase 5

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase PAK 5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 317 amino acids
Theoretical weight: 36.25 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9P286 (Residues: 425-719; Coverage: 41%)
Gene names: KIAA1264, PAK5, PAK7
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: C2
Unit cell:
a: 98.661Å b: 56.599Å c: 120.764Å
α: 90° β: 103.13° γ: 90°
R-values:
R R work R free
0.155 0.154 0.185
Expression system: Escherichia coli BL21(DE3)