PDBe 2eyn

X-ray diffraction
1.8Å resolution

Crystal structure of the actin-binding domain of human alpha-actinin 1 at 1.8 Angstrom resolution


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Alpha-actinin-1 Chain: A
Molecule details ›
Chain: A
Length: 234 amino acids
Theoretical weight: 26.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P12814 (Residues: 30-253; Coverage: 25%)
Gene name: ACTN1
Sequence domains: Calponin homology (CH) domain
Structure domains: Calponin-like domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-BM
Spacegroup: P21212
Unit cell:
a: 53.007Å b: 111.066Å c: 31.549Å
α: 90° β: 90° γ: 90°
R R work R free
0.194 0.184 0.216
Expression system: Escherichia coli BL21(DE3)