› 2eyi

X-ray diffraction
1.7Å resolution

Crystal structure of the actin-binding domain of human alpha-actinin 1 at 1.7 Angstrom resolution

Released:
DOI: 10.2210/pdb2eyi/pdb
PDB entry 2eyi coloured by chain, front view.
PDB entry 2eyi coloured by chain, side view.
PDB entry 2eyi coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the actin-binding domain of alpha-actinin 1: evaluating two competing actin-binding models.
Borrego-Diaz E, Kerff F, Lee SH, Ferron F, Li Y, Dominguez R
J Struct Biol 155 230-8 (2006)
PMID: 16698282

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146323 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-actinin-1 Chain: A
Molecule details ›
Chain: A
Length: 234 amino acids
Theoretical weight: 26.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12814 (Residues: 30-253; Coverage: 25%)
Gene name: ACTN1
Sequence domains: Calponin homology (CH) domain
Structure domains: Calponin-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-BM
Spacegroup: P21212
Unit cell:
a: 56.763Å b: 110.899Å c: 34.91Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.183 0.205
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

Actin and Actin-Binding Proteins.
Pollard TD. (2016)
5 more

10 mentions without citation

Quantitative assessment of protein structural models by comparison of H/D exchange MS data with exchange behavior accurately predicted by DXCOREX.
Liu et al. (2012)
9 more