Structure analysis

The NMR ensemble structure of the Itk SH2 domain bound to a phosphopeptide

Solution NMR
Source organism: Mus musculus
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero dimer

Binding statistics and energies are not available for this assembly

Macromolecules

Chain: A
Length: 109 amino acids
Theoretical weight: 12.56 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q03526 (Residues: 238-344; Coverage: 17%)
Gene names: Emt, Itk, Tlk, Tsk
Pfam: SH2 domain
InterPro:
CATH: SHC Adaptor Protein
SCOP: SH2 domain

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Chain: B
Length: 8 amino acids
Theoretical weight: 795 Da
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: Q60787 (Residues: 143-148; Coverage: 1%)
Gene name: Lcp2

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