PDBe 2esw

X-ray diffraction
2.01Å resolution

Atomic structure of the N-terminal SH3 domain of mouse beta PIX,p21-activated kinase (PAK)-interacting exchange factor

Source organism: Mus musculus

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Rho guanine nucleotide exchange factor 7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 61 amino acids
Theoretical weight: 6.97 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q9ES28 (Residues: 164-220; Coverage: 7%)
Gene names: Arhgef7, Kiaa0142, Pak3bp
Sequence domains: Variant SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P3221
Unit cell:
a: 88.287Å b: 88.287Å c: 40.558Å
α: 90° β: 90° γ: 120°
R R work R free
0.256 0.232 0.254
Expression system: Escherichia coli BL21(DE3)