PDBe 2ekx

Solution NMR

Solution structure of the human BMX SH2 domain

Released:
Source organism: Homo sapiens
Entry authors: Kasai T, Koshiba S, Watanabe S, Harada T, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. 
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytoplasmic tyrosine-protein kinase BMX Chain: A
Molecule details ›
Chain: A
Length: 110 amino acids
Theoretical weight: 12.4 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P51813 (Residues: 291-393; Coverage: 15%)
Gene name: BMX
Sequence domains: SH2 domain
Structure domains: SHC Adaptor Protein

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, restrainted molecular dynamics
Expression system: Not provided