Function and Biology

Structural characterization of the tetrameric form of the major cat allergen fel D 1

Source organism: Felis catus
Biochemical function: steroid binding
Biological process: not assigned
Cellular component: extracellular space

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF09252
Domain description: Allergen Fel d I-B chain
Occurring in:
  1. Major allergen I polypeptide chain 1; Major allergen I polypeptide chain 2
The deposited structure of PDB entry 2ejn contains 2 copies of Pfam domain PF09252 (Allergen Fel d I-B chain) in Major allergen I polypeptide chain 1. Showing 1 copy in chain A.

PF01099
Domain description: Uteroglobin family
Occurring in:
  1. Major allergen I polypeptide chain 1; Major allergen I polypeptide chain 2
The deposited structure of PDB entry 2ejn contains 2 copies of Pfam domain PF01099 (Uteroglobin family) in Major allergen I polypeptide chain 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR016126
Domain description: Secretoglobin
Occurring in:
  1. Major allergen I polypeptide chain 1; Major allergen I polypeptide chain 2
IPR006178
Domain description: Major allergen I polypeptide chain 1
Occurring in:
  1. Major allergen I polypeptide chain 1; Major allergen I polypeptide chain 2
IPR035960
Domain description: Secretoglobin superfamily
Occurring in:
  1. Major allergen I polypeptide chain 1; Major allergen I polypeptide chain 2
IPR015332
Domain description: Major allergen I polypeptide chain 2-like
Occurring in:
  1. Major allergen I polypeptide chain 1; Major allergen I polypeptide chain 2

Structure domain

CATH CATH domain
1.20.920.50
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Histone Acetyltransferase; Chain A
Homology: Histone Acetyltransferase; Chain A
Occurring in:
  1. Major allergen I polypeptide chain 1; Major allergen I polypeptide chain 2
The deposited structure of PDB entry 2ejn contains 2 copies of CATH domain 1.20.920.50 (Histone Acetyltransferase; Chain A) in Major allergen I polypeptide chain 1. Showing 1 copy in chain A.
SCOP SCOP annotation
48202
Class: All alpha proteins
Fold: Uteroglobin-like
Superfamily: Uteroglobin-like
Occurring in:
  1. Major allergen I polypeptide chain 1; Major allergen I polypeptide chain 2
The deposited structure of PDB entry 2ejn contains 4 copies of SCOP domain 48202 (Uteroglobin-like) in Major allergen I polypeptide chain 1. Showing 2 copies in chain A.