› 2egy

X-ray diffraction
2.67Å resolution

Crystal structure of LysN, alpha-aminoadipate aminotransferase (substrate free form), from Thermus thermophilus HB27

Released:
DOI: 10.2210/pdb2egy/pdb
PDB entry 2egy coloured by chain, front view.
PDB entry 2egy coloured by chain, side view.
PDB entry 2egy coloured by chain, top view.
Source organism: Thermus thermophilus HB27
Entry authors: Tomita T, Miyazaki T, Miyagawa T, Fushinobu S, Kuzuyama T, Nishiyama M

Function and Biology Details

Reaction catalysed: 
L-2-aminoadipate + 2-oxoglutarate = 2-oxoadipate + L-glutamate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180893 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
2-aminoadipate transaminase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 397 amino acids
Theoretical weight: 43.9 KDa
Source organism: Thermus thermophilus HB27
Expression system: Escherichia coli
UniProt:
  • Canonical: Q72LL6 (Residues: 1-397; Coverage: 100%)
Gene names: TT_C0043, lysN
Sequence domains: Aminotransferase class I and II
Structure domains:

Ligands and Environments


Cofactor: Ligand PLP 4 x PLP
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: P21
Unit cell:
a: 56.415Å b: 138.51Å c: 111.745Å
α: 90° β: 100.21° γ: 90°
R-values:
R R work R free
0.213 0.213 0.294
Expression system: Escherichia coli

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