PDBe 2e5k

Solution NMR

Solution structure of SH3 domain in Suppressor of T-cell receptor signaling 1

Released:
Source organism: Homo sapiens
Entry authors: Sukegawa S, Tsuda K, Muto Y, Inoue M, Kigawa T, Terada T, Shirouzu M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate. 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ubiquitin-associated and SH3 domain-containing protein B Chain: A
Molecule details ›
Chain: A
Length: 94 amino acids
Theoretical weight: 10.15 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q8TF42 (Residues: 248-328; Coverage: 13%)
Gene names: KIAA1959, STS1, UBASH3B
Sequence domains: Variant SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 94%
Refinement method: torsion angle dynamics, restrainted molecular dynamics
Chemical shifts: BMR10337  
Expression system: Not provided