PDBe 2e4x

X-ray diffraction
2.75Å resolution

Crystal structure of the extracellular region of the group II metabotropic glutamate receptor complexed with 1S,3R-ACPD

Released:
Source organism: Rattus norvegicus
Primary publication:
Structures of the extracellular regions of the group II/III metabotropic glutamate receptors.
Proc. Natl. Acad. Sci. U.S.A. 104 3759-64 (2007)
PMID: 17360426

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Metabotropic glutamate receptor 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 555 amino acids
Theoretical weight: 63.12 KDa
Source organism: Rattus norvegicus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P31422 (Residues: 25-575; Coverage: 64%)
Gene names: Gprc1c, Grm3, Mglur3
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: P21
Unit cell:
a: 83.621Å b: 97.137Å c: 108.158Å
α: 90° β: 92.92° γ: 90°
R-values:
R R work R free
0.228 0.225 0.265
Expression system: Trichoplusia ni