› 2e4f

X-ray diffraction
2.3Å resolution

Crystal Structure of the Cytoplasmic Domain of G-Protein-Gated Inward Rectifier Potassium Channel Kir3.2

Released:
DOI: 10.2210/pdb2e4f/pdb
PDB entry 2e4f coloured by chain, front view.
PDB entry 2e4f coloured by chain, side view.
PDB entry 2e4f coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural Diversity in the Cytoplasmic Region of G Protein-Gated Inward Rectifier K+ Channels
Inanobe A, Matsuura T, Nakagawa A, Kurachi Y
Channels 1 39-45 (2007)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155750 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
G protein-activated inward rectifier potassium channel 2 Chain: A
Molecule details ›
Chain: A
Length: 208 amino acids
Theoretical weight: 23.73 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P48542 (Residues: 199-381; Coverage: 43%)
Gene names: Girk2, Kcnj6, Kcnj7, W
Sequence domains: Inward rectifier potassium channel C-terminal domain
Structure domains: G protein-activated inward rectifier potassium channel 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL44XU
Spacegroup: P4212
Unit cell:
a: 77.173Å b: 77.173Å c: 87.307Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.244 0.244 0.279
Expression system: Escherichia coli

Quick links

Citations

8 mentions without citation

Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease.
Lüscher et al. (2010)
7 more