PDBe 2dvw

X-ray diffraction
2.3Å resolution

Structure of the Oncoprotein Gankyrin in Complex with S6 ATPase of the 26S Proteasome

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
26S proteasome regulatory subunit 6B Chain: B
Molecule details ›
Chain: B
Length: 83 amino acids
Theoretical weight: 9.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P43686 (Residues: 337-418; Coverage: 20%)
Gene names: MIP224, PSMC4, TBP7
Structure domains: Helicase, Ruva Protein; domain 3
26S proteasome non-ATPase regulatory subunit 10 Chain: A
Molecule details ›
Chain: A
Length: 231 amino acids
Theoretical weight: 25.09 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Z2X2 (Residues: 1-231; Coverage: 100%)
Gene name: Psmd10
Sequence domains: Ankyrin repeats (3 copies)
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B1
Spacegroup: P212121
Unit cell:
a: 45.398Å b: 67.886Å c: 107.767Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.169 0.169 0.238
Expression system: Escherichia coli