PDBe 2dhn

X-ray diffraction
2.2Å resolution

COMPLEX OF 7,8-DIHYDRONEOPTERIN ALDOLASE FROM STAPHYLOCOCCUS AUREUS WITH 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 2.2 A RESOLUTION

Released:

Function and Biology Details

Reactions catalysed:
7,8-dihydroneopterin = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde
7,8-dihydroneopterin = 7,8-dihydromonapterin
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dihydroneopterin aldolase Chain: A
Molecule details ›
Chain: A
Length: 121 amino acids
Theoretical weight: 13.77 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
  • Canonical: P56740 (Residues: 1-121; Coverage: 100%)
Gene name: folB
Sequence domains: Dihydroneopterin aldolase
Structure domains: GTP Cyclohydrolase I, domain 2

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ENRAF-NONIUS FR591
Spacegroup: I422
Unit cell:
a: 62.2Å b: 62.2Å c: 123.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.202 0.298
Expression system: Escherichia coli