› 2dc3

X-ray diffraction
1.68Å resolution

Crystal structure of human cytoglobin at 1.68 angstroms resolution

Released:
DOI: 10.2210/pdb2dc3/pdb
PDB entry 2dc3 coloured by chain, front view.
PDB entry 2dc3 coloured by chain, side view.
PDB entry 2dc3 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
High-resolution structure of human cytoglobin: identification of extra N- and C-termini and a new dimerization mode.
Makino M, Sugimoto H, Sawai H, Kawada N, Yoshizato K, Shiro Y
Acta Crystallogr D Biol Crystallogr 62 671-7 (2006)
PMID: 16699195

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186755 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytoglobin Chains: A, B
Molecule details ›
Chains: A, B
Length: 193 amino acids
Theoretical weight: 21.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8WWM9 (Residues: 1-190; Coverage: 100%)
Gene names: CYGB, STAP
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

2 bound ligands:
Ligand HEM 2 x HEM
Ligand ACY 1 x ACY
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL45PX
Spacegroup: C2
Unit cell:
a: 78.53Å b: 52.76Å c: 83.44Å
α: 90° β: 87.75° γ: 90°
R-values:
R R work R free
0.142 0.14 0.181
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

5 review citations

Mammalian nerve globins in search of functions.
Ascenzi et al. (2014)
4 more

12 mentions without citation

Emerging perspectives on cytoglobin, beyond NO dioxygenase and peroxidase.
Mathai et al. (2020)
11 more