PDBe 2ct1

Solution NMR

Solution Structure of the zinc finger domain of Transcriptional repressor CTCF protein

Released:
Source organism: Homo sapiens
Entry authors: Miyamoto K, Koshiba S, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcriptional repressor CTCF Chain: A
Molecule details ›
Chain: A
Length: 77 amino acids
Theoretical weight: 8.5 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P49711 (Residues: 399-462; Coverage: 9%)
Gene name: CTCF
Sequence domains: Zinc finger, C2H2 type
Structure domains: Classic Zinc Finger

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 90%
Refinement method: torsion angle dynamics
Chemical shifts: BMR11316  
Expression system: Not provided