PDBe 2chz

X-ray diffraction
2.6Å resolution

A pharmacological map of the PI3-K family defines a role for p110alpha in signaling: The structure of complex of phosphoinositide 3-kinase gamma with inhibitor PIK-93

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: C2
Unit cell:
a: 144.025Å b: 68.114Å c: 106.351Å
α: 90° β: 95.21° γ: 90°
R-values:
R R work R free
0.246 0.244 0.302
Expression system: Spodoptera frugiperda