PDBe 2chl

X-ray diffraction
1.95Å resolution

Structure of casein kinase 1 gamma 3

Source organism: Homo sapiens
Entry authors: Bunkoczi G, Salah E, Rellos P, Das S, Fedorov O, Savitsky P, Gileadi O, Sundstrom M, Edwards A, Arrowsmith C, Ugochukwu E, Weigelt J, von Delft F, Knapp S

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Casein kinase I isoform gamma-3 Chain: A
Molecule details ›
Chain: A
Length: 351 amino acids
Theoretical weight: 41.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
  • Canonical: Q9Y6M4 (Residues: 35-362; Coverage: 73%)
Gene name: CSNK1G3
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FRE
Spacegroup: P3121
Unit cell:
a: 55.802Å b: 55.802Å c: 219.707Å
α: 90° β: 90° γ: 120°
R R work R free
0.186 0.183 0.234
Expression system: Escherichia coli BL21