Assemblies
Assembly Name:
Caspase-3 and peptide
Multimeric state:
hetero dodecamer
Accessible surface area:
36893.67 Å2
Buried surface area:
39397.85 Å2
Dissociation area:
9,455.77
Å2
Dissociation energy (ΔGdiss):
43.84
kcal/mol
Dissociation entropy (TΔSdiss):
63.21
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-154799
Macromolecules
Chain: A
Length: 147 amino acids
Theoretical weight: 16.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam: Caspase domain
InterPro:
Length: 147 amino acids
Theoretical weight: 16.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P42574 (Residues: 29-175; Coverage: 53%)
Pfam: Caspase domain
InterPro:
- Peptidase C14 family
- Caspase-like domain superfamily
- Peptidase C14A, caspase catalytic domain
- Peptidase C14, p20 domain
- Peptidase C14, caspase domain
- Peptidase family C14A, His active site
- Peptidase family C14A, cysteine active site
Chain: B
Length: 103 amino acids
Theoretical weight: 11.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam: Caspase domain
InterPro:
Length: 103 amino acids
Theoretical weight: 11.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P42574 (Residues: 176-277; Coverage: 37%)
Pfam: Caspase domain
InterPro:
- Caspase-like domain superfamily
- Peptidase C14A, caspase catalytic domain
- Peptidase C14, caspase domain
- Peptidase C14, caspase non-catalytic subunit p10
Chain: I
Length: 5 amino acids
Theoretical weight: 881 Da
Source organism: Homo sapiens
Expression system: Not provided
Length: 5 amino acids
Theoretical weight: 881 Da
Source organism: Homo sapiens
Expression system: Not provided
