PDBe 2c30

X-ray diffraction
1.6Å resolution

Crystal Structure Of The Human P21-Activated Kinase 6

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase PAK 6 Chain: A
Molecule details ›
Chain: A
Length: 321 amino acids
Theoretical weight: 36.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NQU5 (Residues: 383-681; Coverage: 44%)
Gene names: PAK5, PAK6
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P212121
Unit cell:
a: 59.781Å b: 66.674Å c: 96.999Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.197 0.222
Expression system: Escherichia coli